Updates From NIH
Great News! Automated eRA Email Notification Asking for Just-in-Time Information to be Retired October 1, 2024
The automated email sent by eRA requesting Just-in-Time information for an application will be retired on October 1, 2024. This email is sent from era-notify@mail.nih.gov for all applications with an overall impact score of 30 or less. The rest of the JIT process remains the same:
- Official notification of the need for JIT material(s) will continue to be sent directly by NIH staff from the awarding Institute/Center to those who are required to provide the material(s).
- The JIT link to submit the materials, when requested, will also continue to be available in eRA Commons until the application is awarded. The JIT link is accessed:
- By SOs, on the Status Results screen by clicking on the three-dot ellipsis in the Application/Award ID column and choosing JIT from the dropdown menu.
- By PIs, on the Status screen, by expanding a grant application and clicking the JIT link in the Available Actions column.
As a reminder, a request for JIT information is not a Notice of Award, nor should it be construed as an indicator of possible funding by the NIH. If you have any additional questions, contact the Grants Management Specialist assigned to your application.
The NIH Grants Policy Statement, Section 2.5.1 Just-in-Time Procedures, as well as resources on the eRA and NIH Grants and Funding webpages, will be updated to reflect this process update.
For full details of this change, review the NIH Notice.
NIH’s Adoption of Common Forms for Biographical Sketch and Current and Pending (Other) Support
This NIH Guide Notice informs the extramural community of NIH’s adoption of Common Forms for Biographical Sketch and Current and Pending (Other) Support to be used with all applications and Research Performance Progress Report(s) (RPPRs) by May 25, 2025. The Common Forms represent a collaborative effort between federal research agencies to ensure standard disclosure requirements as outlined in the National Security Presidential Memorandum - 33. The approved Common Forms for Biographical Sketch and Current and Pending (Other) Support (OMB Number 3145-0279 managed by the U.S. National Science Foundation (NSF)), can be accessed at NSF’s website at NSTC Research Security Subcommittee NSPM-33 Implementation Guidance Disclosure Requirements & Standardization.
Review the full notice and the NIH webpage dedicated to this change.
Implementation Update for Data Management and Access Practices Under the NIH Genomic Data Sharing Policy
The National Institutes of Health (NIH) is updating two practices under the NIH Genomic Data Sharing (GDS) Policy to continue to promote responsible data management and access. These changes are to ensure GDS Policy implementation continues to evolve alongside changing practices for collecting, sharing, and using controlled-access human genomic data and include (1) modernizing security standards provided in the “NIH Security Best Practices for Controlled-Access Data Subject to the NIH Genomic Data Sharing (GDS) Policy” and (2) establishing minimum expectations for access to controlled-access data by developers. This implementation update will take effect on January 25, 2025.
NIH Notice NOT-OD-24-157 provides full background and implementation details.
NIH Grant Closeout Process Webinar: Administrative and Financial Essentials
Are you involved in the closeout of NIH grants? If so, it’s important to understand the administrative and financial responsibilities involved to ensure compliance with NIH policies.
To help you gain a better understanding of the required reports and related policies, NIH experts invite you to participate in a webinar on Tuesday, September 17, 2024. Gain insights on topics such as:
- Final Research Performance Progress Report (RPPR)
- Final Invention Statement
- Final Federal Financial Report (FFR)
- And more!
Registration is required for the webinar, and you can find the registration link on the NIH webpage.
Events
Sept. 12, 2024 - Brody Lecture
In Partnership with the Distinguished Biomedical Scholars Lecture Series
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Zachary Knight, PhD
"Neural Mechanisms That Control Appetite"
Investigator, Howard Hughes Medical Institute
Professor, Department of Physiology
University of California, San Francisco
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Sept. 24, 2024 - Distinguished Mentor Award Celebration
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Daniel Tranel, PhD
Awardee
Professor, Department of Neurology
University of Iowa
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Antonio Damasio, MD, PhD
Lecturer - "On the Biology of Consciusness"
Director, Brain and Creativity Institute
University of Southern California
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Oct. 17, 2024 - Distinguished Biomedical Scholars Lecture
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Jared Rutter, PhD
"Metabolism, Cellular Decisions and the Language That Unites Them"
Investigator, Howard Hughes Medical Institute
Distinguished Professor, Department of Biochemistry
University of Utah
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Core Updates
Celeste Ptak, PhD, named as Assistant Director to the Proteomics Facility
Celeste Ptak, PhD, begins as the Assistant Director to the Proteomics Facility on September 3.
Dr. Ptak received her doctorate in Chemistry with a specialization in Mass Spectrometry from the University of Virginia where she worked under Professor Donald Hunt, a pioneer in the field of mass spectrometry. Her experience working under Dr. Hunt and Dr. Jeff Shabanowitz, his lab manager, allowed her to learn proteomics from the ground up. Her research focused on quantitative proteomics and optimizing methods for the identification of phosphorylated peptides by mass spectrometry. After graduation, Dr. Ptak worked as an Application Scientist for Advion BioSciences, a research support specialist in the Proteomics and Metabolomics Facility at Cornell University and taught in the Chemistry Department at Ithaca College before coming to the University of Iowa in 2022. While at the University of Iowa, Celeste has operated and maintained the Bruker timsTOF mass spectrometer while also optimizing methodology for label-free quantitation. She has also begun taking over managerial tasks and organizing standard operating procedures and training materials. She looks forward to more opportunities to assist with research projects. Congratulations, Dr. Ptak!
Going forward, questions about the facility and projects should be directed to com-proteomics@uiowa.edu.
Bruker timsTOF HT mass spectrometer has been installed in the Proteomics Facility.
Staff are testing the performance of the spectrometer and will be prepared to run samples for customers starting in October of 2024. Please direct questions to com-proteomics@uiowa.edu.
SERCC Hosts Virtual Office Hours
Cytek Amnis ImageStreamX MkII Imaging Cytometer Coming Soon to Flow Cytometry
The Flow Cytometry Facility has successfully received NIH S10 grant funding for a Cytek Amnis ImageStreamX MkII imaging cytometer equipped with 405nm, 488nm, 561nm, and 642nm lasers plus two CCD-TDI cameras enabling 12 channel detection and 20X, 40X, and 60X objective lenses. The ImageStream will allow investigators to combine the quantitative traits of flow cytometry (speed, sensitivity, and phenotypic ability) with the qualitative traits of microscopy (detailed imagery, morphological information, and functional insight), which is technology that is not currently available at the University of Iowa. This unique combination of technical capabilities has wide-ranging applications that are not possible using either method alone.
The Cytek Amnis ImageStreamX MkII is capable of a wide range of applications, including:
- Apoptosis: Detecting and analyzing programmed cell death.
- Cell Cycle Analysis: Studying the different phases of the cell cycle.
- Co-localization: Identifying the spatial overlap of different fluorescent markers within cells.
- Internalization: Measuring the uptake of substances by cells.
- Nuclear Localization: Tracking the movement of molecules into the nucleus.
- Shape Change: Observing changes in cell morphology.
- Spot Counting: Counting discrete spots of fluorescence within cells.
- Cell-Cell Interactions: Analyzing interactions between different cells.
- Phagocytosis: Studying the engulfment of particles by cells.
- Autophagy: Investigating the process by which cells degrade and recycle their own components.
- Stem Cell Differentiation: Monitoring the differentiation process of stem cells.
- Characterization of Circulating Tumor Cells: Identifying and analyzing tumor cells in the bloodstream.
The instrument will ideally be installed in the Flow Cytometry facility near the end of September or early October.
Any questions please contact Heath Vignes: heath-vignes@uiowa.edu
ImageStream | Cytek Biosciences
